Posted on September 29, 2007 in HCC by adminNo Comments »

If had liver cancer patients are the first physical fatigue, even if the patient to lie down town, it can not eliminate fatigue, which can not eliminate the burnout and fatigue is a common symptom general liver. Human intake of food, the heat will be intestinal absorption, some transported to the liver, liver through storage, auto body to the various cells. If liver cancer invasion by, the entire fuel supply would be reduced, as the result of heat inadequate, causing physical burnout and fatigue easily. If burnout or just lazy, may also be suffering from the flu or fatigue. Few people realize that they may have had liver cancer, the disease that has been delayed.

If cancer is somewhat larger, can cause flu darkest Department boring, or upper right abdomen feeling pain. Not even the extent of pain there will be a compression and discomfort. Suffering from liver cancer, stomach disorders are often caused symptoms, including loss of appetite, nausea, after eating breakfast flu and stomach discomfort flu. If weight loss, when there are unexplained fever and jaundice, must go to the hospital for alpha-fetoprotein (afp), b-, ct, x-liver diagnosis methods such as angiography.

The early symptoms of liver cancer are: abdominal swelling flu, abdominal pain, sense of general malaise, anorexia, jaundice and skin itching.

Posted on September 29, 2007 in HCC by adminNo Comments »

     A pathological manifestations: normal liver size, quality scans. The main feature is active fiber hyperplasia, a fiber beam sizes, renewable single nodule uneven, only a few false lobular form.
     2, the functional performance: moderate liver dysfunction, such as: ALT, AST mildly elevated without jaundice, light to moderate reduce serum protein, serum - time pro normal, normal blood ammonia.
     3, clinical symptoms: can no obvious clinical symptoms, also may be in the leans.

      With the onset of cirrhosis than those in the general course of slow, insidious 3-5 years or more than 10 years ago, its clinical manifestations can be divided into decompensated liver function and the decompensated stage, but two boundaries is not obvious or overlap.
     One, decompensated liver function lesser symptoms often lack specificity, the lack of fatigue, anorexia and dyspepsia based. There are nausea, repulsive oil, abdominal flatulence, abdominal discomfort, pain and diarrhea.
     2, decompensated liver function symptoms significantly.
(1) Liver dysfunction clinical manifestations:
     1. General systemic symptoms and poor nutritional status, weight loss fatigue, deep, severe, debilitating and bedridden. Rough dry skin, and leans gloomy dark complexion. Often anemia, anemia, nutritional, night blindness, and the swelling and Polyneuritis.
     2. Gastrointestinal symptoms.
     3. Bleeding and anemia.
     4. Endocrine disorders.
     (2) levy of portal hypertension clinical manifestations constitutes portal hypertension sign a three clinical manifestations splenomegaly, and the establishment of collateral circulation and open, ascites, have important clinical significance. Collateral circulation particularly the establishment and opening of the diagnosis of value.
Clinical manifestations of liver cirrhosis
General hepatitis and cirrhosis patients systemic symptoms, there are many performance features of the liver, different patients can be very different. In addition to the usual clinical manifestations of chronic hepatitis, its main clinical features of liver dysfunction and portal hypertension. But there are also some occult patients with cirrhosis without any clinical manifestations, even in laparotomy surgery, autopsy or other examination found.
     (1) general symptoms
Typical patients and the general condition of both poor nutrition, weight loss, deep, poor appetite, self-induced fatigue weakness, abdominal distension and most of the afternoon and evening of the case, there are left and right quarter of help in pain or discomfort, the sense of falling, some patients have irregular fever, mouth Cape consciously, leads to weight, Jin Yi led to high-fat food such as diarrhea.
(2) symptoms and signs
     1. Skin changes in some patients with pigmented leans filthy, there are stained. Superior vena cava in the drainage areas that spider Germany. Hands can be showed liver palms, telangiectasia also more common, mainly in the dry skin of patients with cirrhosis of the face and thigh-skin. Some patients with abdominal vein evident, and can re-shaped with varicose.
     2. In the early cirrhosis of liver and spleen, liver enlargement can be advanced smaller, more hard and texture, surface and the price or distribution of small nodules. The liver size, hardness, surface is smooth, and the liver fatty infiltration and the number of liver regeneration, fibrous tissue hyperplasia and the extent of the contraction. The majority of patients with varying degrees of the license. Decompensated liver function generally levy no ascites.
     3. Liver dysfunction clinical performance
     (1) Huang yield: jaundice patients with cirrhosis of liver cells is more, the event should be considered: 1 indicated the activity of hepatitis diseases. ② intrahepatic cholestasis: cirrhosis, bile production and secretion of various aspects of the process could occur obstacles caused cholestasis. There are three main aspects: sodium-potassium ATPase dysfunction; Transporter cells inhibited; Liver cell membrane permeability changes. ③ serious liver function failure: Lesions often said to have developed end-stage, accompanied hepatic encephalopathy poor prognosis. ④ cirrhosis have occurred on the basis of malignant transformation: Depth should dramatically enhance tumor suspected hepatic portal transfer from biliary obstruction.
     (2) tendency to bleeding and anemia: liver function decline on prothrombin and other coagulation factor synthesis; At the same time because of hypersplenism and bone marrow megakaryocyte void formation. Lead thrombocytopenia; Platelet membrane phospholipids, glycoprotein structure abnormal adhesion and aggregation and low, it often Purple epidemic, nose bleeding gums and gastrointestinal bleeding. Patients have varying degrees of anemia, and more from a lack of nutrition, poor intestinal absorption, hypersplenism and gastrointestinal bleeding and other factors.
     (3) gastrointestinal symptoms: loss of appetite was diminished sense of abdominal discomfort after eating and guns bulging, flu can be severe nausea, vomiting or even the fat and protein tolerance of difference. For patients with ascites and gastrointestinal flu gas and abdominal distension, there will be advanced in the dark intestinal toxicity. Generation and the symptoms of gastrointestinal congestion, edema, inflammation caused by digestion and absorption of intestinal dysfunction and disorder-related groups. Also very common chronic cholecystitis, its symptoms and the symptoms of cirrhosis difficult to distinguish.

Posted on September 29, 2007 in HCC by adminNo Comments »

1. Hepatocellular carcinoma (HCC) is one of our common malignancy, misprision of onset, once treatment is a more advanced, and advanced clinical manifestations diversification, the lack of specificity, making it easy for misdiagnosis.
2.84% with cirrhosis of the liver cancer patients based on the occurrence of liver cancer prevention to the prevention of chronic liver disease.
3. AFP detection is the best diagnosis of primary hepatocellular carcinoma, the most sensitive, most specifically of the early diagnostic methods, and other methods matched correctly positive rate of 90%, but still 30% to 40% of the patients with negative or low concentration, an average of misdiagnosis rate of 43.9% summing up the experience and lessons misdiagnosis, the rate of liver cancer diagnosis has important significance.
4. Liver cancer is cancer saying stresses the King, with the development of science and technology is the treatment of liver cancer has made encouraging progress in the world, compared with other cancers, the world, more and more people will use Active Botanicals treatment of liver cancer, treatment efficacy, with a smooth, five-year survival rate of liver cancer in China a world leader .
5. After diagnosis of liver cancer in the most advanced, often coupled with patients with cirrhosis, therefore, limited opportunities for surgery, chemotherapy (chemotherapy) on the long-term effects of poor liver cancer, and the greater toxicity, liver is a delicate organ, generally not for radiotherapy treatment and broad prospects of modern medicine .
6. “Excessive” chemotherapy “blind” not appropriate radiotherapy and hepatic artery embolization, and easily lead to jaundice, ascites and liver failure and even life-threatening, it is highly vigilant.
7. In patients with hepatocellular carcinoma ascites indicates jaundice, liver failure, should be prohibited at this time by chemotherapy (including chemotherapy), diuretics are often ineffective activity Botanicals - “Anticancer water-law” is the treatment of choice.
8. HCC patients with poor liver function reserve, in the selection of drugs including anti-inflammatory agents, anti-cancer medicine and other therapeutic measures should be taken fully into account this point, or patients with heavier, and even endanger the lives of their own instead of HCC.
9. Two patients each year, a review of the liver, liver function and B-AFP, if not intensified, such as bloating, pain in symptoms such as jaundice, ascites timely and competent doctor.
10. Large Clinical Practice has proved that targeted specific individuals, the treatment of cancer throughout the course of treatment, protective and treatment, scientific, comprehensive treatment of moderate activity Botanicals smooth treatment lifesaving cancer treatment philosophy is a magic weapon for successful treatment of liver cancer.
11. HCC prognosis of many factors, mass, larger, higher AFP obvious pain, portal vein thrombosis, embolism or thrombosis formation of the basis of serious liver cirrhosis, liver failure or signs indicate serious illness, clinicians should be alert.
12. HCC died of a non-refractory disease, mitigation treatment more important, as can spend the first year of stable, with greater hope of survival. Patients survived more than five years is not uncommon.
1. Hepatocellular carcinoma (HCC) is our common malignant swelling of 2.84% based on liver cancer patients with cirrhosis, liver cancer prevention
3.AFP detection is the diagnosis of primary hepatocellular carcinoma, the most-best four. Liver cancer is cancer saying stresses the King, with the science and technology
5. Liver cancer is diagnosed in most of the late addition of six permanent. “Excessive” chemotherapy “blind” not appropriate radiotherapy and liver
7. In patients with hepatocellular carcinoma ascites indicates jaundice, liver failure, 8. HCC patients with poor liver function reserve, in the selection of drugs
9. Two patients each year, a review of the liver, liver function B-10. Clinical Practice has proved that large targeted, individualized treatment

Posted on September 17, 2007 in HCC by adminNo Comments »

A more accurate kill cancer cells, and significantly reduce the side effects of chemotherapy new program recently in Wuhan Xiehe Hospital for formal clinical. Practice has shown that, “chemosensitivity screening” approach can significantly improve the effectiveness of chemotherapy patients with hepatocellular carcinoma. This method commonly used chemotherapy and the difference is that the cells will be “the last radical” after resection, not eager to chemotherapy, but the first with liver cancer cells in vitro, with a variety of commonly used chemotherapy drugs in these cancer cells from the patients screened with obvious anti-liver cancer Effects of chemotherapy drugs to be developed for patients with a personalized program of chemotherapy. Liver cancer is the most common cancer in China is one of our patients died from the second malignancies. Currently, surgery is still the primary hepatocellular carcinoma radical means, but because of rapid development of hepatocellular carcinoma, even in patients undergoing excision as a residual liver and outside often difficult to detect small metastatic lesions, surgery can not completely resected tumors, chemotherapy will have to rely on diffusion to kill cancer cells in vivo. However, each with different characteristics of liver cancer, the sensitivity of different chemotherapy drugs are different, and commonly used chemotherapy regimen means there are certain blindness to the effect of each patient are different. If every application with the same or similar program of chemotherapy, some patients may effect of the drug sensitive and good, and some patients on these drugs for cancer is not sensitive to chemotherapy control, killing liver cancer cells, on the contrary, the inherent toxicity of chemotherapy drugs will seriously undermine its own role in the immune function , and hematopoietic system, liver function, renal function, and other important organs causing serious injury.

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